Development of new self-assembled cationic amino liposomes for efficient gene delivery. (23rd April 2020)
- Record Type:
- Journal Article
- Title:
- Development of new self-assembled cationic amino liposomes for efficient gene delivery. (23rd April 2020)
- Main Title:
- Development of new self-assembled cationic amino liposomes for efficient gene delivery
- Authors:
- Wu, Yihang
Xiong, Yue
Wang, Ling
Zhou, Quanming
Li, Linxian
Levkin, Pavel A.
Davidson, Gary
Gao, Liqian
Deng, Wenbin - Abstract:
- Abstract : A library of lipidoids self-assembling to liposomes exhibits excellent transfection efficiency in HEK 293T cells and mESCs with low cytotoxicity. Abstract : A library of 83 structurally diverse cationic amino liposomes is rationally designed and parallelly synthesized for the transfection of plasmid DNA and siRNA. Our designed self-assembled liposomes not only exhibit excellent transfection efficiency in HEK 293T cells and mouse embryonic stem cells, but also show low cytotoxicity.
- Is Part Of:
- Biomaterials science. Volume 8:Number 11(2020)
- Journal:
- Biomaterials science
- Issue:
- Volume 8:Number 11(2020)
- Issue Display:
- Volume 8, Issue 11 (2020)
- Year:
- 2020
- Volume:
- 8
- Issue:
- 11
- Issue Sort Value:
- 2020-0008-0011-0000
- Page Start:
- 3021
- Page End:
- 3025
- Publication Date:
- 2020-04-23
- Subjects:
- Biomedical materials -- Periodicals
610.28 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/bm ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/d0bm00331j ↗
- Languages:
- English
- ISSNs:
- 2047-4830
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 2087.724000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 13841.xml