Early osteoblastic activity on TiO2 thin films decorated with flower-like hierarchical Au structures. Issue 48 (5th August 2020)

• Record Type: Journal Article
• Authors: Kalantzis, Spyridon; Veziroglu, Salih; Kohlhaas, Theresa; Flörke, Christian; Mishra, Yogendra Kumar; Wiltfang, Jörg; Açil, Yahya; Faupel, Franz; Aktas, Oral Cenk; Gülses, Aydin
• Is Part Of: RSC advances. Volume 10:Issue 48(2020)
• Page Start: 28935
• Page End: 28940
• Publication Date: 2020-08-05
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/d0ra05141a
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : Flower-like hierarchical Au structures, composed of micro- and nanoscale features, lead to higher number of filopodia formation on TiO2 thin films. Abstract : Titanium alloys are the most commonly used dental and orthopedic implant materials due to their proven biocompatibility and mechanical properties. The native oxide layer (TiO2 layer) formed on such Ti-based implants acts as the self-protecting layer against possible ion release. Increasing the oxide layer thickness further on such TiO2 implants even opens the triggering of the osseointegration process if the oxide layer is having a certain degree of roughness, preferably higher. This work reports a novel photocatalytic patterning of sputter deposited TiO2 layers with flower-like Au structures to enhance the early osteoblastic activity. The prepared hierarchical Au structures, composed of micro- and nanoscale features on the top, lead to improved number of filopodia formation. This suggest that proposed Au–TiO2 surface may foster the cell attachment and as well as cell proliferation.