Silver-catalyzed direct C–H oxidative carbamoylation of quinolines with oxamic acids. Issue 14 (30th March 2020)

• Record Type: Journal Article
• Authors: Yuan, Jin-Wei; Chen, Qian; Li, Chuang; Zhu, Jun-Liang; Yang, Liang-Ru; Zhang, Shou-Ren; Mao, Pu; Xiao, Yong-Mei; Qu, Ling-Bo
• Is Part Of: Organic & biomolecular chemistry. Volume 18:Issue 14(2020)
• Page Start: 2747
• Page End: 2757
• Publication Date: 2020-03-30
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/d0ob00358a
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : A facile and highly efficient method has been successfully developed for the synthesis of 2-carbamoylated quinolines. The current reaction exhibits broad substrate scope, good functional group compatibility, and good to excellent yields. Abstract : A silver-catalyzed efficient and direct C–H carbamoylation of quinolines with oxamic acids to access carbamoylated quinolines has been developed through oxidative decarboxylation reaction. The reaction proceeds smoothly over a broad range of substrates with excellent functional group tolerance and excellent yields under mild conditions.