Chemically synthesized circular RNAs with phosphoramidate linkages enable rolling circle translation. Issue 46 (5th May 2020)
- Record Type:
- Journal Article
- Title:
- Chemically synthesized circular RNAs with phosphoramidate linkages enable rolling circle translation. Issue 46 (5th May 2020)
- Main Title:
- Chemically synthesized circular RNAs with phosphoramidate linkages enable rolling circle translation
- Authors:
- Nakamoto, Kosuke
Abe, Naoko
Tsuji, Genichiro
Kimura, Yasuaki
Tomoike, Fumiaki
Shimizu, Yoshihiro
Abe, Hiroshi - Abstract:
- Abstract : Circular RNA without a stop codon enables rolling circle translation. we carried out one-pot chemical synthesis of circular RNA from RNA fragments. The synthesized circular RNAs acted as translation templates, despite the presence of unnatural phosphoramidate linkages. Abstract : Circular RNA without a stop codon enables rolling circle translation. To produce circular RNAs, we carried out one-pot chemical synthesis of circular RNA from RNA fragments with the use of an EDC/HOBt-based chemical ligation reaction. The synthesized circular RNAs acted as translation templates, despite the presence of unnatural phosphoramidate linkages.
- Is Part Of:
- Chemical communications. Volume 56:Issue 46(2020)
- Journal:
- Chemical communications
- Issue:
- Volume 56:Issue 46(2020)
- Issue Display:
- Volume 56, Issue 46 (2020)
- Year:
- 2020
- Volume:
- 56
- Issue:
- 46
- Issue Sort Value:
- 2020-0056-0046-0000
- Page Start:
- 6217
- Page End:
- 6220
- Publication Date:
- 2020-05-05
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/d0cc02140g ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 13837.xml