A fluorescent molecular rotor probe for tracking plasma membranes and exosomes in living cells. Issue 60 (26th June 2020)

• Record Type: Journal Article
• Authors: Feng, Ling; Xie, Yusheng; Au-Yeung, Sung King; Hailu, Hagos Birhanu; Liu, Zhiyang; Chen, Qingxin; Zhang, Jie; Pang, Qiuxiang; Yao, Xi; Yang, Mengsu; Zhang, Liang; Sun, Hongyan
• Is Part Of: Chemical communications. Volume 56:Issue 60(2020)
• Page Start: 8480
• Page End: 8483
• Publication Date: 2020-06-26
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d0cc03069d
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A rotor-based fluorescent probe to label exosomes in living cells. Abstract : A rotor-based probe MRMP-1 was designed and synthesized. MRMP-1 can bind to plasma membranes very quickly and stably with remarkable fluorescence enhancement. It can be used to monitor the dynamic changes in cell membranes in real-time under stimuli conditions. Importantly, MRMP-1 is the first rotor-based fluorescent sensor to label exosomes in living cells.