Copper(i) catalyzed synthesis of selanyl methylene 4-chromanol and aurone derivatives. Issue 24 (10th June 2020)

• Record Type: Journal Article
• Authors: Sahoo, Sushree Ranjan; Sarkar, Debayan; Henkel, Felix; Reuter, Hans
• Is Part Of: Organic & biomolecular chemistry. Volume 18:Issue 24(2020)
• Page Start: 4619
• Page End: 4627
• Publication Date: 2020-06-10
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/d0ob00632g
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : An efficient copper-catalyzed cyclization cascade approach towards highly functionalized methylene 4-chromanol and aurone derivatives has been developed from reactions of ynols via 6- exo-dig and 5- exo-dig cyclization respectively. Abstract : An efficient copper-catalyzed cyclization cascade approach towards highly functionalized methylene 4-chromanol and aurone derivatives has been developed from reactions of ynols via 6- exo-dig and 5- exo-dig cyclization respectively. The catalysis involves alkyne activation via diorgano-diselenides and also their regioselective incorporation into the methylene 4-chromanol and aurone derivative core and is an open-air transformation.