Fluoroalkyl sulfides as photoredox-active coupling reagents for alkene difunctionalization. Issue 66 (17th July 2020) - Kosobokov, Mikhail D.
Abstract : A visible-light-promoted fluoroalkylation-thiolation of alkenes is described. Abstract : A visible-light-promoted fluoroalkylation-thiolation of alkenes is described. A 4-tetrafluoropyridinylthio fragment serves as a photoredox-active group in the initiation step and undergoes a radical group transfer, which is important for the reaction efficiency. In the primary products, the pyridinylthio substituent may be further functionalized via radical processes or an aromatic substitution reaction.