A fentanyl vaccine constructed upon opsonizing antibodies specific for the Galα1–3Gal epitope. Issue 48 (12th May 2020)
- Record Type:
- Journal Article
- Title:
- A fentanyl vaccine constructed upon opsonizing antibodies specific for the Galα1–3Gal epitope. Issue 48 (12th May 2020)
- Main Title:
- A fentanyl vaccine constructed upon opsonizing antibodies specific for the Galα1–3Gal epitope
- Authors:
- Wang, Jiaxing
Ellis, Beverly
Zhou, Bin
Eubanks, Lisa M.
Blake, Steven
Janda, Kim D. - Abstract:
- Abstract : A double-conjugate fentanyl vaccine leveraging preformed anti-Gal antibodies significantly reduced the pain-relieving effect of fentanyl in mice. Abstract : A double conjugation strategy was implemented to produce an anti-fentanyl vaccine, which was predicated upon preformed-antibody-assisted antigen presentation. The new vaccine was found to reduce the psychoactive effects of fentanyl without the addition of the immunostimulant CpG oligodeoxynucleotide.
- Is Part Of:
- Chemical communications. Volume 56:Issue 48(2020)
- Journal:
- Chemical communications
- Issue:
- Volume 56:Issue 48(2020)
- Issue Display:
- Volume 56, Issue 48 (2020)
- Year:
- 2020
- Volume:
- 56
- Issue:
- 48
- Issue Sort Value:
- 2020-0056-0048-0000
- Page Start:
- 6551
- Page End:
- 6554
- Publication Date:
- 2020-05-12
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/d0cc02107e ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 13820.xml