Acylation/cyclization of 1, 6-dienes with ethers under catalyst- and base-free conditions. Issue 12 (8th June 2020)

• Record Type: Journal Article
• Authors: Huang, Xun-Jie; Qin, Fu-Hua; Liu, Yi; Wu, Shi-Ping; Li, Qiang; Wei, Wen-Ting
• Is Part Of: Green chemistry. Volume 22:Issue 12(2020)
• Page Start: 3952
• Page End: 3955
• Publication Date: 2020-06-08
• Subjects: Environmental chemistry -- Industrial applications -- Periodicals; Environmental management -- Periodicals; 660
• DOI: 10.1039/d0gc00865f
• Languages: English
• ISSNs: 1463-9262

Abstract

Abstract : A concise and eco-friendly acylation/cyclization of 1, 6-dienes with linear ethers under catalyst- and base-free conditions has been developed. Abstract : A concise and eco-friendly acylation/cyclization of 1, 6-dienes with linear ethers under catalyst- and base-free conditions has been developed. tert -Butyl hydroperoxide (TBHP)-promoted tandem cleavage of C(sp 3 )–H and C(sp 3 )–O bonds of linear ethers is the key in this process, which provides a straightforward and efficient method to realize acylation reaction. The significant advantages of this method include catalyst- and base-free, mild reaction conditions, high scalability, operational simplicity, ease of scale-up, dual roles of ethers and controllable synthesis.