Clinical usefulness of very high serum soluble interleukin-2 receptor levels for the detection of tuberculous peritonitis in a patient with chronic myelogenous leukemia. Issue 10 (October 2020)

• Record Type: Journal Article
• Authors: Moriguchi, Makoto; Koh, Hideo; Hayashi, Tetsuya; Okamura, Hiroshi; Nanno, Satoru; Nakashima, Yasuhiro; Nakane, Takahiko; Imoto, Waki; Yamada, Koichi; Kakeya, Hiroshi; Hino, Masayuki; Nakamae, Hirohisa
• Is Part Of: Journal of infection and chemotherapy. Volume 26:Issue 10(2020:Oct.)
• Page Start: 1054
• Page End: 1057
• Publication Date: 2020-10
• Subjects: Soluble interleukin-2 receptor -- Chronic myelogenous leukemia -- Tuberculous peritonitis -- Tuberculosis -- Ascites; Chemotherapy -- Periodicals; Infection -- Periodicals; Communicable diseases -- Chemotherapy -- Periodicals; 615.5805
• DOI: 10.1016/j.jiac.2020.05.001
• Languages: English
• ISSNs: 1341-321X

Abstract

Abstract: Tuberculous peritonitis is difficult to diagnose due to the disadvantages of ascitic culture and peritoneal biopsy. Although previous reports suggested that very high serum soluble interleukin-2 receptor (sIL-2R) levels may reflect the clinical activity of tuberculosis, little is known about the diagnostic utility of serum sIL-2R for tuberculous peritonitis. We describe a case of tuberculous peritonitis with chronic myelogenous leukemia. The abnormally high serum sIL-2R value and negative findings for other possible causes including lymphoma suggested tuberculous peritonitis and we administered anti-tuberculosis treatment before definitive diagnosis. Abnormally high serum sIL-2R levels may contribute to earlier diagnosis of tuberculous peritonitis, along with ruling out other potential differential diagnoses.