Antiretroviral treatment for HIV infection: Swedish recommendations 2019. Issue 5 (3rd May 2020)

• Record Type: Journal Article
• Authors: Eriksen, Jaran; Carlander, Christina; Albert, Jan; Flamholc, Leo; Gisslén, Magnus; Navér, Lars; Svedhem, Veronica; Yilmaz, Aylin; Sönnerborg, Anders
• Is Part Of: Infectious diseases. Volume 52:Issue 5(2020)
• Page Start: 295
• Page End: 329
• Publication Date: 2020-05-03
• Subjects: Antiretroviral -- HIV -- treatment guidelines -- Sweden -- adult -- paediatric; Communicable diseases -- Periodicals; Communicable Diseases -- Periodicals; Communicable diseases; Periodicals; 616.9
• DOI: 10.1080/23744235.2019.1707867
• Languages: English
• ISSNs: 2374-4235

Abstract

Abstract: The Swedish Reference Group for Antiviral Therapy (RAV) published recommendations for the treatment of HIV infection in this journal most recently in 2017. An expert group under the guidance of RAV here provides updated recommendations. The most important updates in the present guidelines are the following: (a) The risk of HIV transmission through condomless sex from individuals with fully suppressed HIV viral load is effectively zero. (b) Pre-exposure prophylaxis (PrEP) is recommended for groups with a high risk of HIV infection. (c) Since the last update, two new substances have been registered: bictegravir and doravirine. (d) Dual treatment may be an alternative in selected patients, using lamivudine + dolutegravir or lamivudine + boosted darunavir/atazanavir. As with previous publications, recommendations are evidence-graded in accordance with the Oxford Centre for Evidence Based Medicine. This document does not cover treatment of opportunistic infections and tumours.