Cancer during HIV infection. Issue 2 (28th January 2020)

• Record Type: Journal Article
• Authors: da Silva Neto, Marinho Marques; Brites, Carlos; Borges, Álvaro H.
• Other Names: Andersen Åse Bengård guestEditor.; Nejsum Lene N. guestEditor.
• Is Part Of: Apmis. Volume 128:Issue 2(2020)
• Page Start: 121
• Page End: 128
• Publication Date: 2020-01-28
• Subjects: HIV -- AIDS -- cancer -- screening -- antiretroviral therapy; Pathology -- Periodicals; Microbiology -- Periodicals; Immunology -- Periodicals; 572
• DOI: 10.1111/apm.13020
• Languages: English
• ISSNs: 0903-4641

Abstract

Abstract : HIV+ persons have a significantly increased risk of cancer when compared to the general population. The excess cancer risk observed during HIV infection is particularly higher for infection‐related malignancies. Mechanisms underlying this remain unclear, but both HIV‐related and HIV‐unrelated factors have been postulated to play a role. Here, we (i) review newly published data on cancer burden in the setting of HIV infection with a focus on HIV‐related risk factors for cancer; (ii) discuss emerging data on cancer among HIV+ persons living in low‐ and middle‐income countries; and (iii) review guideline recommendations for cancer screening among HIV+ persons and discuss ongoing studies investigating strategies for cancer screening among HIV+ patients.