Preparation and Degradation Behaviors of Poly(L-lactide-co-glycolide-co-ε-caprolactone)/1, 4-butanediamine Modified Poly(lactic-co-glycolic acid) Blend Film. Issue 8 (2nd August 2020)

• Record Type: Journal Article
• Authors: Zhou, Ziwei; Zhou, Zhihua; Liu, Wenjuan; Huang, Tianlong; Zhao, Yanmin; Chen, Ping; Wang, Dan; Fang, Jianjun
• Is Part Of: Journal of macromolecular science. Volume 59:Issue 8(2020)
• Page Start: 491
• Page End: 501
• Publication Date: 2020-08-02
• Subjects: Blending polymer -- poly(L-lactide-co-glycolide-co-ε-caprolactone) -- poly(lactic-co-glycolic acid) -- 14-butanediamine; Polymerization -- Periodicals; Polymers -- Periodicals; 530.413
• DOI: 10.1080/00222348.2020.1746027
• Languages: English
• ISSNs: 0022-2348

Abstract

Abstract: Polymer blending is an attractive method for producing new polymer materials with excellent properties. In this work the blended polymers were prepared from poly(L-lactide-co-glycolide-co-ε-caprolactone) and 1, 4-butanediamine modified poly(lactic-co-glycolic acid) (PLLGC/BMPLGA). The hydrophilicity was studied by static water contact angle tests. The in-vitro degradation behaviors of the PLLGC/BMPLGA blended films were investigated during various degradation periods. The results showed that the introduction of the PLLGC reduced the hydrophilicity and degradation rate of the blended polymers while improved the tensile strength and elongation percentage. Therefore, we suggest the blends of the PLLGC and BMPLGA could supply a potential biomaterial for application in the medical field for use as tissue engineering scaffolds or drug delivery.