18F-FDG PET/CT Brain in a Case of Agrammatic/Nonfluent Variant of Primary Progressive Aphasia (Broca's Aphasia). (May 2020)

• Record Type: Journal Article
• Authors: Kousik, Vankadari; Mittal, Bhagwant Rai; Kumar, Rajender; Singh, Harmandeep; Goyal, Manoj
• Is Part Of: Clinical nuclear medicine. Volume 45:Number 5(2020)
• Publication Date: 2020-05
• Subjects: frontal aslant tract -- primary progressive aphasia -- 18F-FDG PET/CT brain; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000003008
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: Primary progressive aphasia is a neurodegenerative variant of frontotemporal lobe degeneration presenting with isolated selective impairment of language domain, not secondarily due to stroke. We present a case of middle-aged female patient who underwent 18 F-FDG PET of the brain for evaluating progressively declining speaking ability associated with altered fluency of speech and occasional mutism. 18 F-FDG PET revealed asymmetric hypometabolism involving the left inferior frontal gyrus along with left anterior cingulate gyrus suggestive of Broca's aphasia.