68Ga–Prostate-Specific Membrane Antigen Uptake in Dissecting Abdominal Aortic Aneurysm. (June 2020)

• Record Type: Journal Article
• Authors: Wong, Veronica Chi Ken; Yip, Joshua Wei Liang; Stevanovic, Amanda; Le, Ken; Mansberg, Robert
• Is Part Of: Clinical nuclear medicine. Volume 45:Number 6(2020)
• Publication Date: 2020-06
• Subjects: 68Ga-PSMA -- atherosclerosis -- dissecting abdominal aortic aneursym -- prostate cancer; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000002972
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: An 81-year-old man with prostate adenocarcinoma (Gleason 4 + 3 = 7) treated with brachytherapy and intermittent androgen deprivation therapy was referred for serial 68 Ga–prostate-specific membrane antigen (PSMA-HBED-CC) PET/CT scans for rising prostate-specific antigen. Findings were suggestive of local prostatic recurrence and nodal metastases. An incidental PSMA-avid focus was noted in the anterior wall of an infrarenal aortic aneurysm, with a contrast-enhanced hyperdense region surrounded by a semilunar hypodense region anteriorly, consistent with enlarging dissecting thrombus. Increased PSMA avidity in atherosclerotic hypertensive lesions may relate to active plaque instability, indicating a need for further evaluation.