Outcomes in Pregnancies With a Confined Placental Mosaicism and Implications for Prenatal Screening Using Cell-Free DNA. Issue 7 (July 2020)

• Record Type: Journal Article
• Authors: Grati, Francesca Romana; Ferreira, Jose; Benn, Peter; Izzi, Claudia; Verdi, Federica; Vercellotti, Elena; Dalpiaz, Cristina; D'Ajello, Patrizia; Filippi, Elisa; Volpe, Nicola; Malvestiti, Francesca; Maggi, Federico; Simoni, Giuseppe; Frusca, Tiziana; Cirelli, Gaetana; Bracalente, Gabriella; Re, Antonino Lo; Surico, Daniela; Ghi, Tullio; Prefumo, Federico
• Is Part Of: Obstetrical & gynecological survey. Volume 75:Issue 7(2020)
• Publication Date: 2020-07
• Subjects: Obstetrics -- Periodicals; Gynecology -- Periodicals; Generative organs, Female -- Surgery -- Periodicals; 618
• DOI: 10.1097/01.ogx.0000688044.66625.e4
• Languages: English
• ISSNs: 0029-7828

Abstract

Abstract : (Abstracted from Genet Med 2020;22:309–316) The most common type of confined placental mosaicism (CPM), the presence of a chromosomal abnormality in the placenta but not in the fetus, involves trisomy/disomy. Confined placental mosaicism occurs in 97% of rare autosomal trisomy (RAT) cases detected by chorionic villus sampling (CVS).