Single-Cell Analysis of Human Ovarian Cortex Identifies Distinct Cell Populations But No Oogonial Stem Cells. Issue 6 (June 2020)

• Record Type: Journal Article
• Authors: Wagner, Magdalena; Yoshihara, Masahito; Douagi, Iyadh; Damdimopoulos, Anastasios; Panula, Sarita; Petropoulos, Sophie; Lu, Haojiang; Pettersson, Karin; Palm, Kerstin; Katayama, Shintaro; Hovatta, Outi; Kere, Juha; Lanner, Fredrik; Damdimopoulou, Pauliina
• Is Part Of: Obstetrical & gynecological survey. Volume 75:Issue 6(2020)
• Publication Date: 2020-06
• Subjects: Obstetrics -- Periodicals; Gynecology -- Periodicals; Generative organs, Female -- Surgery -- Periodicals; 618
• DOI: 10.1097/OGX.0000000000000805
• Languages: English
• ISSNs: 0029-7828

Abstract

Abstract : (Abstracted from Nat Commun 2020;11:1147) In the female fetus, oogonia derived from fetal germ cells (FGCs) form primordial follicles that remain dormant until reactivation in the postnatal ovary. The reserve of primordial follicles in the ovarian cortex determines the fertile lifespan, and its depletion marks the beginning of menopause.