Fusion 68Ga–Prostate-Specific Membrane Antigen PET/MRI on Postoperative Surveillance of Juvenile Nasal Angiofibroma. (July 2020)

• Record Type: Journal Article
• Authors: Sakthivel, Pirabu; Thakar, Alok; Arunraj, Sreedharan Thankarajan; Bhalla, Ashu Seith; Kumar, Rakesh
• Is Part Of: Clinical nuclear medicine. Volume 45:Number 7(2020)
• Publication Date: 2020-07
• Subjects: angiofibroma -- juvenile nasopharyngeal angiofibroma -- MRI -- PSMA PET; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000003041
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: Prostate-specific membrane antigen (PSMA) is expressed universally in juvenile nasopharyngeal angiofibroma (JNA). As contrast enhancement of postoperative scar is common with contrast-enhanced MRI (CEMRI), diagnosis of residual/recurrent JNA remains perplexing. Prostate-specific membrane antigen PET targets only the neovasculature and may aid in resolving this dilemma. Positive contrast enhancement on CEMRI was noted in a patient after 30 years of initial surgery, simulating recurrence. However, there was no abnormal uptake in PSMA scan, which was confirmed by biopsy as postoperative fibrosis. 68 Ga-PSMA PET/MRI fusion may be an easy and novel technique to aid in differentiating residual/recurrent disease from surgical site reparative tissue.