A review of implantable pulsatile blood pumps: Engineering perspectives. Issue 9 (September 2020)

• Record Type: Journal Article
• Authors: Wu, Tingting; Khir, Ashraf W; Kütting, Maximilian; Du, Xinli; Lin, Hao; Zhu, Yuxin; Hsu, Po-Lin
• Is Part Of: International journal of artificial organs. Volume 43:Issue 9(2020)
• Page Start: 559
• Page End: 569
• Publication Date: 2020-09
• Subjects: Mechanical circulatory support device -- pulsatile blood pump -- pumping mechanism -- blood-contact -- ventricular assist devices -- total artificial heart; Artificial organs -- Periodicals; 617.956
• DOI: 10.1177/0391398820902470
• Languages: English
• ISSNs: 0391-3988

Abstract

It has been reported that long-term use of continuous-flow mechanical circulatory support devices (CF-MCSDs) may induce complications associated with diminished pulsatility. Pulsatile-flow mechanical circulatory support devices (PF-MCSDs) have the potential of overcoming these shortcomings with the advance of technology. In order to promote in-depth understanding of PF-MCSD technology and thus encourage future mechanical circulatory support device innovations, engineering perspectives of PF-MCSD systems, including mechanical designs, drive mechanisms, working principles, and implantation strategies, are reviewed in this article. Some emerging designs of PF-MCSDs are introduced, and possible elements for next-generation PF-MCSDs are identified.