Risk Factors, Etiologies, and Screening Tools for Sepsis in Pregnant Women: A Multicenter Case-Control Study. Issue 2 (June 2020)

• Record Type: Journal Article
• Authors: Bauer, M.E.; Housey, M.; Bauer, S.T.; Behrmann, S.; Chau, A.; Clancy, C.; Clark, E.A.S.; Einav, S.; Langen, E.; Leffert, L.; Lin, S.; Madapu, M.; Maile, M.D.; McQuaid-Hanson, E.; Priessnitz, K.; Sela, H.Y.; Shah, A.; Sobolewski, P.; Toledo, P.; Tsen, L.C.; Bateman, B.T.
• Is Part Of: Obstetric anesthesia digest. Volume 40:Issue 2(2020)
• Publication Date: 2020-06
• Subjects: Infection and Sepsis -- Nonobstetric Maternal Disease; Anesthesia in obstetrics -- Periodicals; Anesthesia in obstetrics -- Abstracts -- Periodicals; 617.968205
• DOI: 10.1097/01.aoa.0000661332.57510.93
• Languages: English
• ISSNs: 0275-665X

Abstract

Abstract : ( Anesth Analg . 2019;129:1613–1620) Sepsis is the third leading cause of maternal morbidity and mortality, making up ∼12.7% of pregnancy-related deaths. Early identification and prompt treatment of patients can improve maternal outcomes. However, it is difficult to diagnose sepsis in pregnancy because physiological changes of pregnancy can mimic the signs of sepsis. The quick Sequential (Sepsis-related) Organ Failure Assessment (qSOFA) criteria, systemic inflammatory response syndrome (SIRS) criteria, and the maternal early warning (MEW) criteria all provide different screening methods that may be useful, but their validity for the identification of early sepsis in pregnancy are unknown. Therefore, the primary objective of this multicenter case-control study was to evaluate the performance characteristics of the SIRS, qSOFA, and MEW criteria for identifying cases of early maternal sepsis during perinatal hospitalization. In addition, the authors sought to identify which of the 3 screening criteria is best used in maternal sepsis.