L-Citrulline Supports Vascular and Muscular Benefits of Exercise Training in Older Adults. Issue 3 (July 2020)

• Record Type: Journal Article
• Authors: Figueroa, Arturo; Jaime, Salvador J.; Morita, Masahiko; Gonzales, Joaquin U.; Moinard, Christophe
• Is Part Of: Exercise and sport sciences reviews. Volume 48:Issue 3(2020:Jul.)
• Publication Date: 2020-07
• Subjects: arterial aging -- vascular dysfunction -- sarcopenia -- oral L-citrulline -- nitric oxide -- exercise performance -- muscle protein synthesis; Sports -- Physiological aspects -- Periodicals; Exercise -- Physiological aspects -- Periodicals; Sports medicine -- Periodicals; 612.76
• DOI: 10.1249/JES.0000000000000223
• Languages: English
• ISSNs: 0091-6331

Abstract

Abstract : Age-associated reduction in endothelial nitric oxide (NO) synthesis contributes to the development of cardiovascular diseases and sarcopenia. L-Citrulline is a precursor of NO with the ability to improve vascular function and muscle protein synthesis. We hypothesize that vascular and muscular benefits associated with oral L-citrulline supplementation might be augmented by concomitant supplementation with exercise training in older adults. Abstract : Oral L-citrulline and exercise training influence vascular and muscular aging via improved nitric oxide bioavailability and muscle protein synthesis.