Role of Static and Dynamic Intra-abdominal Pressure Monitoring in Acute Pancreatitis: A Prospective Study on Its Impact. Issue 5 (May 2020)

• Record Type: Journal Article
• Authors: Goenka, Mahesh Kumar; Goenka, Usha; Afzalpurkar, Shivaraj; Tiwari, Subhash Chandra; Agarwal, Rachit; Tiwary, Indrajeet Kumar
• Is Part Of: Pancreas. Volume 49:Issue 5(2020)
• Publication Date: 2020-05
• Subjects: static IAP -- dynamic IAP -- intra-abdominal hypertension -- abdominal compartment syndrome; Pancreas -- Diseases -- Periodicals; Pancreas -- Periodicals; Neuroendocrine tumors -- Periodicals; 616.37005
• DOI: 10.1097/MPA.0000000000001544
• Languages: English
• ISSNs: 0885-3177

Abstract

Abstract : Objective: This study was aimed to determine the relationship between static and dynamic intra-abdominal pressure (IAP) with the mortality and outcome of acute pancreatitis. Methods: From July 2017 to December 2018, 150 patients admitted at the Institute of Gastrosciences and Liver and diagnosed as acute pancreatitis were included in the study. Intra-abdominal pressure was measured for the first few days, and mean value of day 1 (static IAP) and highest value on day 2 and day 3 (dynamic IAP) were calculated and categorized into intra-abdominal hypertension and abdominal compartment syndrome. Results: A statistical relationship was observed between static and dynamic IAP with the severity and mortality of acute pancreatitis. Both static and dynamic IAPs tended to be higher in nonsurvivors (83.33% and 88.88%, respectively) compared with survivors (51.51% and 63.63%, respectively). Higher IAP had more severe disease. However, IAP did not correlate with the evidence of sepsis or serum procalcitonin levels. Conclusion: Determination of static IAP is an easy, useful, and inexpensive method to determine and predict the mortality of acute pancreatitis. Prevention and/or early detection of intra-abdominal hypertension helps in reducing the mortality in acute pancreatitis.