Intravenous isavuconazole can be administered 5 days-a-week. A possibility suggested by a real-life observation. (18th May 2020)

• Record Type: Journal Article
• Authors: Castagnola, Elio; Mesini, Alessio; Saffioti, Carolina; Barco, Sebastiano; Bandettini, Roberto; Dallorso, Sandro; Carrega, Giuliana; Miano, Maurizio; Palmisani, Elena; Dufour, Carlo
• Is Part Of: Journal of chemotherapy. Volume 32:Number 4(2020)
• Page Start: 217
• Page End: 218
• Publication Date: 2020-05-18
• Subjects: Isavuconazole -- pediatrics intermittent therapy -- plasma concentrations; Chemotherapy -- Periodicals; Drug Therapy -- Periodicals; 615.58
• DOI: 10.1080/1120009X.2020.1755591
• Languages: English
• ISSNs: 1120-009X

Abstract

Abstract : In this report it is shown that intravenous formulation of isavuconazole could be administered 5/7 days a week in patients who can not swallow capsules, once the steady state has been stably reached and maintained, thanks to its very long half-life. In this case TDM should be highly recommended.