Acanthophoraine A, a new pyrrolidine alkaloid from the red alga Acanthophora spicifera. Issue 14 (17th July 2020)

• Record Type: Journal Article
• Authors: Lin, Jia-Li; Liang, Yong-Qian; Liao, Xiao-Jian; Yang, Jian-Ting; Li, Dai-Chun; Huang, Yu-Ling; Jiang, Zhi-Hui; Xu, Shi-Hai; Zhao, Bing-Xin
• Is Part Of: Natural product research. Volume 34:Issue 14(2020)
• Page Start: 2065
• Page End: 2070
• Publication Date: 2020-07-17
• Subjects: Red alga -- Acanthophora spicifera -- alkaloids; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2019.1569008
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: A new pyrrolidine alkaloid, acanthophoraine A (1 ), along with six known alkaloids (2 –7 ), had been isolated from the red alga Acanthophora spicifera . The structures of these compounds were identified by spectroscopic analyses. The absolute configuration of 1 was established by ECD calculation. Compound 1 represents the first example of N -isobutyl pyrrolidone with an urea arm. The antimicrobial activity of 1 was also evaluated.