Trichosordarin A, a norditerpene glycoside from the marine-derived fungus Trichoderma harzianum R5. Issue 14 (17th July 2020)

• Record Type: Journal Article
• Authors: Liang, Xiao-Rui; Ma, Xin-Yue; Ji, Nai-Yun
• Is Part Of: Natural product research. Volume 34:Issue 14(2020)
• Page Start: 2037
• Page End: 2042
• Publication Date: 2020-07-17
• Subjects: Trichoderma harzianum -- norditerpene -- trichosordarin A; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2019.1574782
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: A new sordarin derivative, trichosordarin A (1 ), with a unique norditerpene aglycone was isolated from the culture of a marine-sediment-derived fungal strain, Trichoderma harzianum R5. Its structure and relative configuration were unequivocally identified by a combination of 1D/2D NMR, IR, and mass spectrometric methods. Compound 1 was assayed to be toxic to the marine zooplankton Artemia salina . Graphical Abstract: