Influence of titanium and zirconia modified surfaces for rapid healing on adhesion and biofilm formation of Staphylococcus epidermidis. (September 2020)

• Record Type: Journal Article
• Authors: Kunrath, Marcel F.; Monteiro, Marina S.G.; Gupta, Saurabh; Hubler, Roberto; de Oliveira, Sílvia D.
• Is Part Of: Archives of oral biology. Volume 117(2020)
• Publication Date: 2020-09
• Subjects: Titanium -- Zirconia -- Surfaces -- Staphylococcus epidermidis -- Implants -- Infection; Mouth -- Periodicals; Mouth -- Diseases -- Periodicals; Dentistry -- Periodicals; Electronic journals; 617.6005
• DOI: 10.1016/j.archoralbio.2020.104824
• Languages: English
• ISSNs: 0003-9969

Abstract

Highlights: Ti and Zr have similar antibacterial properties. Alterations of nanomorphology, roughness, and wettability influence bacterial adhesion. High roughness and hydrophilicity increase S. epidermidis interaction with surfaces. Abstract: Objective: Surface alterations have been employed to enhance the osseointegration process in biomedical implants. However, these modifications may influence bacterial adhesion in different ways. Therefore, this study developed five different surfaces and evaluated the Staphylococcus epidermidis growth in early (1 h) and late (24 h) contact. Design: The Titanium (Ti) and Zirconia (Zr) surfaces were divided in five groups and characterized concerning your morphology, roughness, wettability and chemical surface composition. Then, were evaluated regarding bacterial adhesion and biofilm formation/thickness, viability and morphology. Results: Different topographies were manufactured resulting in a variety of combinations of surface properties. High roughness showed significantly higher bacterial adhesion in 1 h, while high hydrophilicity revealed greater bacterial proliferation in 24 h. Morphological changes were not found visually, however the viability test showed some cell membrane damage in the Ti micro and nano groups. Conclusions: Finally, surface distinct properties influence the growth of S. epidermidis independent of the based-material. Furthermore, some surface properties require precautions for use in contaminated sites according to the increased adhesion of S. epidermidis presented when in contact.