Effect of antioxidant/reducing agents on the initial and long-term bonding performance of a self-etch adhesive to caries-affected dentin with and without smear layer-deproteinizing. (October 2020)

• Record Type: Journal Article
• Authors: Prasansuttiporn, Taweesak; Thanatvarakorn, Ornnicha; Mamanee, Teerapong; Hosaka, Keiichi; Tagami, Junji; Foxton, Richard M.; Nakajima, Masatoshi
• Is Part Of: International journal of adhesion & adhesives. Volume 102(2020)
• Publication Date: 2020-10
• Subjects: A.self-etch adhesive -- A.MMP inhibitors -- C.micro-tensile -- D.durability -- Anti-oxidant/reducing agent; Adhesion -- Periodicals; Adhesives -- Periodicals; Adhésion (Physique) -- Périodiques; Adhésifs -- Périodiques; Adhesie; Kleefstoffen; Adhesion; Adhesives; Periodicals; 668.3
• DOI: 10.1016/j.ijadhadh.2020.102648
• Languages: English
• ISSNs: 0143-7496

Abstract

Abstract: This study aimed to evaluate the effect of a reducing agent containing p -toluenesulfinic acid sodium salt (Accel®) and plant-extract antioxidant (rosmarinic acid solution) on the bonding durability of a self-etch adhesive to caries-affected dentin with and without smear layer-deproteinizing with NaOCl solution. The caries-affected dentin were assigned to pretreatment of smear layer-deproteinizing with NaOCl solution or none, then subdivided to reducing agent/antioxidant treatment with p -toluenesulfinic acid sodium salt or rosmarinic acid solution or none. After bonding with 2-step self-etch adhesive and restoring with resin composite, the specimens were stored in artificial saliva for 24 h or 1 year. The microtensile bond strength (μTBS) were analyzed by three-way ANOVA with post-hoc Tukey's test and t -test ( p < 0.05). The collagen-fibril status at hybridized complex was observed under TEM. The results showed that μTBS to caries-affected dentin significantly decreased after 1-year of storage ( p < 0.05). Smear layer-deproteinizing with NaOCl significantly decreased μTBS to caries-affected dentin despite eliminating hybridized smear layer, however a subsequent application with p -toluenesulfinic acid sodium salt and rosmarinic acid solution significantly increased initial bond strengths ( p < 0.05) and maintained the bond strengths after 1-year of storage ( p > 0.05), with preservation of collagen-fibril integrity within authentic hybrid layer. Therefore, the additional application of p -toluenesulfinic acid sodium salt and rosmarinic acid solution after smear layer-deproteinizing with NaOCl could improve initial and long-term bond strengths of a self-etch adhesive to caries-affected dentin.