Ameliorative effects of paricalcitol against 1800-MHz mobile phone radiation-induced skin damage in rats. Issue 9 (26th November 2019)

• Record Type: Journal Article
• Authors: Aktas, Savas; Comelekoglu, Ulku; Demirbag, Burcu; Kibar, Deniz; Uzun, Cosar; Yildirim, Metin; Ozdemir, Erkin; Korunur Engiz, Begüm; Sogut, Fatma; Akar, Aysegül; Yalin, Serap
• Is Part Of: Toxicological and environmental chemistry. Volume 101:Issue 9/10(2019)
• Page Start: 508
• Page End: 525
• Publication Date: 2019-11-26
• Subjects: 1800-MHz RF -- paricalcitol -- skin -- oxidative stress; Toxicology -- Periodicals; Environmental chemistry -- Periodicals; 571.95
• DOI: 10.1080/02772248.2020.1721500
• Languages: English
• ISSNs: 0277-2248

Abstract

Abstract: This study aimed to evaluate the protective role of paricalcitol, a vitamin D analog, against hazardous effects of 1800-MHz radiofrequency (RF) radiation on the skin of male Wistar albino rats exposed one h/day for 4 weeks. The maximum specific absorption rate was calculated as 0.0042 W/kg. Superoxide dismutase and catalase activity, collagen bundle thickness, breaking force, energy, and stress were decreased, while malondialdehyde level and mast cell number were increased. The exposure to 1800-MHz RF radiation caused a reduction in skin biomechanical quality through oxidative stress and mast cell activation. The administration of paricalcitol caused a significant improvement.