Eslicarbazepine for focal epilepsy and acute intermittent porphyria. Issue 3 (28th July 2020)

• Record Type: Journal Article
• Authors: Herrera‐Fortin, Tamara; Pana, Raluca; Wesolowska, Ewa; Bourré‐Tessier, Josiane; Nguyen, Dang K.
• Is Part Of: Epileptic disorders. Volume 22:Issue 3(2020)
• Page Start: 349
• Page End: 352
• Publication Date: 2020-07-28
• Subjects: eslicarbazepine -- carbamazepine -- hepatic porphyria; Epilepsy -- Periodicals; 616.853
• DOI: 10.1684/epd.2020.1171
• Languages: English
• ISSNs: 1294-9361

Abstract

Abstract: Porphyrias are rare genetic disorders which cause a deficiency in the enzymes involved in the biosynthesis of heme. The treatment of epilepsy in patients with acute intermittent porphyria can be difficult since many anticonvulsants can increase heme synthesis and trigger porphyric attacks. We report a patient with focal epilepsy successfully treated with eslicarbazepine without exacerbation of porphyria.