Primary cutaneous marginal zone lymphoma treated with doxycycline in a pediatric patient. Issue 4 (23rd April 2020)

• Record Type: Journal Article
• Authors: Jothishankar, Balaji; Di Raimondo, Cosimo; Mueller, Lisa; Zain, Jasmine; Parekh, Vishwas; Abdulla, Farah
• Is Part Of: Pediatric dermatology. Volume 37:Issue 4(2020)
• Page Start: 759
• Page End: 761
• Publication Date: 2020-04-23
• Subjects: Pediatric dermatology -- Periodicals; Children -- Diseases -- Periodicals; 618.925
• DOI: 10.1111/pde.14165
• Languages: English
• ISSNs: 0736-8046

Abstract

Abstract: We present the third reported case of a primary cutaneous marginal zone lymphoma (PCMZL) treated with doxycycline in a pediatric patient with negative serology for Borrelia burgdorferi . A 14‐year‐old boy presented with multiple asymptomatic erythematous papules and nodules on his extremities and trunk which biopsy confirmed to be PCMZL. He was started on doxycycline and experienced a near‐complete response. Given the favorable side effect profile of doxycycline and the indolent nature of PCMZL, we believe doxycycline is a possible therapy for PCMZL pediatric patients who have widely disseminated cutaneous disease.