Structure of cytochrome b5 unique to tardigrades. (24th July 2020)

• Record Type: Journal Article
• Authors: Fukuda, Yohta; Kim, JeeEun; Inoue, Tsuyoshi
• Is Part Of: Protein science. Volume 29:Number 8(2020)
• Page Start: 1829
• Page End: 1835
• Publication Date: 2020-07-24
• Subjects: cytochrome b5 -- heme -- tardigrade -- X‐ray crystallography; Proteins -- Periodicals; 572.6
• DOI: 10.1002/pro.3896
• Languages: English
• ISSNs: 0961-8368

Abstract

Abstract: Cytochrome b 5 is an essential electron transfer protein, which is ubiquitously found in living systems and involved in wide variety of biological processes. Tardigrades (also known as water bears), some of which are famous for desiccation resistance, have many proteins unique to them. Here, we report spectroscopic and structural characterization of a cytochrome b 5 like protein from one of the desiccation‐tolerant tardigrades, Ramazzottius varieornatus strain YOKOZUNA‐1 ( Rv Cyt b 5 ). A 1.4 Å resolution crystal structure revealed that Rv Cyt b 5 is a new cytochrome b 5 protein specific to tardigrades. Abstract : PDB Code(s): 7BWH ;