Purified and specific cytoplasmic pollen extract: a non-hormonal alternative for the treatment of menopausal symptoms. (3rd March 2020)

• Record Type: Journal Article
• Authors: Genazzani, Andrea; Panay, Nick; Simoncini, Tommaso; Depypere, Herman; Mueck, Alfred; Egarter, Christian; Biglia, Nicoletta; Fait, Tomas; Birkhaeuser, Martin; Skouby, Sven O.; Brincat, Mark; Goldstein, Steven; Ruan, Xiangyan; Celis-Gonzales, Cuauhtémoc; Palacios, Santiago
• Is Part Of: Gynecological endocrinology. Volume 36:Number 3(2020)
• Page Start: 190
• Page End: 196
• Publication Date: 2020-03-03
• Subjects: Purified and specific cytoplasmic pollen extract -- PureCyTonin® -- menopause -- non-hormonal alternative -- hot flushes -- premenstrual syndrome -- Serelys®; Endocrine gynecology -- Periodicals; Generative organs, Female -- Diseases -- Periodicals; 618.1
• DOI: 10.1080/09513590.2020.1722994
• Languages: English
• ISSNs: 0951-3590

Abstract

Abstract: Research into non-hormonal, alternative therapies is necessary for women for whom menopausal hormone therapy is contraindicated or for women who do not wish to take hormones. This review focuses on one such non-hormonal option, namely, purified and specific cytoplasmic pollen extract, or PureCyTonin ® . This extract has been evaluated in several preclinical and clinical studies, where it demonstrated its value as a safe and non-estrogenic alternative for menopause. This review presents the beneficial effects of PureCyTonin ® in the treatment of menopausal symptoms (e.g. hot flushes) in healthy women, as well as in premenstrual syndrome. We discuss the mechanism of action of PureCyTonin ®, an SSRI-'like' therapy. The lack of estrogenic effect demonstrated in preclinical studies suggests that PureCyTonin ® may also be a suitable option for the management of menopausal symptoms in women with breast cancer.