Cyanoacrylate-encapsulated calcium peroxide achieved oxygen-sustained release and promoted wound healing. Issue 11 (23rd July 2020)

• Record Type: Journal Article
• Authors: Zhang, Tao; Han, Zeye; Zhang, Wei; Wang, Jian; Xu, Liang
• Is Part Of: International journal of polymeric materials. Volume 69:Issue 11(2020)
• Page Start: 703
• Page End: 708
• Publication Date: 2020-07-23
• Subjects: Calcium peroxide -- cyanoacrylate -- oxygen release; Polymers -- Periodicals; Plastics -- Periodicals; 620.19205
• DOI: 10.1080/00914037.2019.1600518
• Languages: English
• ISSNs: 0091-4037

Abstract

Abstract: Sustained oxygen release is important to many oxygen-requiring situations. Developing composite materials capable of releasing oxygen in diverse circumstances have potential use in aquaculture, environmental remediation, and wound healing, et al. In this study, a composite material poly-11-CaO2 was developed by encapsulation of calcium peroxide in a biodegradable crosslinking cyanoacrylate (poly-LKJ11). CaO2 physically dispersed inside the polymer depot. Poly-11-CaO2 achieved sustained oxygen release in water environment, that the DO concentration of water could be increased for more than 25 days in a N2 bubbled bottle model. Poly-11-CaO2 could also release oxygen on skin surface, thereafter, a poly-11-CaO2 contained plaster improved dermal wound healing in a rat model. GRAPHICAL ABSTRACT: