Citriperazines A-D produced by a marine algae-derived fungus Penicillium sp. KMM 4672. Issue 8 (17th April 2020)

• Record Type: Journal Article
• Authors: Yurchenko, Anton Nikolaevich; Berdyshev, Dmitry V.; Smetanina, Olga F.; Ivanets, Elena V.; Zhuravleva, Olesya I.; Rasin, Anton B.; Khudyakova, Yuliya V.; Popov, Roman S.; Dyshlovoy, Sergey A.; von Amsberg, Gunhild; Afiyatullov, Shamil Sh.
• Is Part Of: Natural product research. Volume 34:Issue 8(2020)
• Page Start: 1118
• Page End: 1123
• Publication Date: 2020-04-17
• Subjects: Penicillium sp. -- diketopiperazines -- secondary metabolites -- ECD -- TDDFT; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2018.1552696
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: Four new diketopiperazine alkaloids, citriperazines A-D were isolated from algae-derived Penicillium sp. KMM 4672. The structures of compounds 1–4 were determined using spectroscopic methods. The absolute configurations of compounds 1 and 4 were established by comparison of calculated and experimental ECD spectra. The cytotoxicity of compounds 1 –4 against several human prostate cell lines was evaluated. Graphical Abstract: