Fluorescent Determination of Mercury (II) and Glutathione Using Amino-MIL-53(Al) Nanosheets. (21st November 2020)

• Record Type: Journal Article
• Authors: Ren, Meijuan; Wang, Huan; Liu, Yuanyuan; Ma, Qin; Jia, Wenjing; Liu, Mingzhu; Wang, Huiju; Lu, Yongchang
• Is Part Of: Analytical letters. Volume 53:Number 17(2020)
• Page Start: 2700
• Page End: 2714
• Publication Date: 2020-11-21
• Subjects: amino-MIL-53(Al) nanosheets -- fluorescent -- glutathione -- turn-off-on -- Hg2+; Chemistry, Analytic -- Periodicals; Chemistry, Analytic -- Abstracts; 543
• DOI: 10.1080/00032719.2020.1755680
• Languages: English
• ISSNs: 0003-2719

Abstract

Abstract: Amino-MIL-53(Al) nanosheets were synthesized by a hydrothermal reaction and were employed as a fluorescent probe because of their high quantum yield and excellent stability. The amino-MIL-53(Al) nanosheets have a maximum fluorescence emission peak at 435 nm using an excitation wavelength of 335 nm. The fluorescent intensity of luminophor at 435 nm was linearly quenched when mercury (II) (Hg 2+ ) was added, which occurred due to the adsorption of Hg 2+ onto the luminophor surface. Under these conditions, the fluorescent signal of the system is in the "turn-off" state. Following the addition of glutathione (GSH) into the system, the quenched fluorescence intensity may be partially restored based on the reaction between glutathione and Hg 2+ . In this condition, the fluorescent signal of the amino-MIL-53(Al)-Hg 2+ system is in the "turn-on" state. Therefore, the amino-MIL-53(Al) nanosheets were successfully used as a "turn-off-on" fluorescent sensing system to determine the concentrations of Hg 2+ in Tibetan medicine and glutathione in rabbit serum. A good correlation coefficient was obtained between the quenching of the fluorescence intensity of luminophor and the concentration of Hg 2+ using the optimized conditions. A linear range was acquired from 1.96 nM to 38.27 μM with a detection limit of 0.23 nM of Hg 2+ based upon a signal-to-noise ratio of three. For glutathione, the linear dynamic range was from 210 nM to 15.25 μM with a detection limit equal to 8.11 nM based upon a signal-to-noise ratio of three. This developed sensor system has the advantages of high selectivity, favorable sensitivity and simple operation for the determination of Hg 2+ and glutathione in real samples.