Detection, treatment and prevention of endodontic biofilm infections: what's new in 2020?. (3rd March 2020)

• Record Type: Journal Article
• Authors: Abusrewil, Sumaya; Alshanta, Om Alkhir; Albashaireh, Khawlah; Alqahtani, Saeed; Nile, Christopher J.; Scott, James Alun; McLean, William
• Is Part Of: Critical reviews in microbiology. Volume 46:Number 2(2020)
• Page Start: 194
• Page End: 212
• Publication Date: 2020-03-03
• Subjects: Endodontic -- biofilm -- eradication -- prevention; Microbiology -- Periodicals; Microbiology -- Periodicals; Review Literature -- Periodicals; 579
• DOI: 10.1080/1040841X.2020.1739622
• Languages: English
• ISSNs: 1040-841X

Abstract

Abstract: Endodontic disease, a biofilm infection of the root canal space, is a significant cause of dental morbidity worldwide. Endodontic treatment, or root canal treatment, as it is commonly known is founded on the ability to eradicate microbial biofilm infection and prevent re-infection of the highly complex root canal space. Despite many "advances" in clinical endodontics we have seen little improvement in outcomes. The aim of this critical review paper is to provide a contemporary view of endodontic microbiology and biofilm polymicrobiality, provide an understanding of the host response, and how together these impact upon clinical treatment. Ultimately, it is intended to provide insight into novel opportunities and strategies for the future diagnostics, treatment, and prevention of endodontic disease.