Cu-assisted C–N bond formations in six-membered N-heterocycle synthesis. Issue 8 (17th April 2020)

• Record Type: Journal Article
• Authors: Kaur, Navjeet; Ahlawat, Neha; Verma, Yamini; Grewal, Pooja; Bhardwaj, Pranshu; Jangid, Nirmala Kumari
• Is Part Of: Synthetic communications. Volume 50:Issue 8(2020)
• Page Start: 1075
• Page End: 1132
• Publication Date: 2020-04-17
• Subjects: Catalysis -- copper -- heterocycles -- nitrogen -- synthesis -- six-membered heterocycle; Organic compounds -- Synthesis -- Periodicals; Chemistry, Organic; Synthesis; 547.205
• DOI: 10.1080/00397911.2019.1695278
• Languages: English
• ISSNs: 0039-7911

Abstract

Abstract: One of the highly emerging and important aspect of organic chemistry is the metal-catalyzed synthesis of the heterocycles. The methodologies used earlier for its synthesis were less approachable to the organic chemist because of their high cost, highly specified instrumentation and inconvenient methods. For both the stereoselective and regioselective synthesis of six-membered nitrogen-containing heterocycles, cyclic reactions that are Cu-catalyzed have known to be very efficient. The presented review covers the varied applications of Cu as a catalyst and its importance in the formation of six-membered nitrogen-containing heterocycles. The fascinating research that has been done in this area is also enclosed in this review. Graphical Abstract: