UNIT 11.13 Efficient Alignment of Illumina‐Like High‐Throughput Sequencing Reads with the GEnomic Multi‐tool (GEM) Mapper. Issue 1 (19th June 2015)

• Record Type: Journal Article
• Authors: Marco‐Sola, Santiago; Ribeca, Paolo
• Is Part Of: Current protocols in bioinformatics. Volume 50:Issue 1(2015)
• Page Start: 11.13.1
• Page End: 11.13.20
• Publication Date: 2015-06-19
• Subjects: sequencing -- high‐throughput sequencing -- next‐generation sequencing -- bioinformatics -- genomics -- alignment -- mapping -- read mapping -- sequencing read mapping; Bioinformatics -- Laboratory manuals; Nucleotide sequence -- Laboratory manuals; Amino acid sequence -- Laboratory manuals; Base Sequence; Amino Acid Sequence; Computational Biology -- methods; Databases, Genetic; Proteins -- analysis; Sequence Analysis -- methods; Sequence Homology; Amino acid sequence; Bioinformatics; Nucleotide sequence; Laboratory Manuals; Laboratory manuals; 570.285
• DOI: 10.1002/0471250953.bi1113s50
• Languages: English
• ISSNs: 1934-3396

Abstract

Abstract : Modern Illumina‐like high‐throughput sequencing machines allow the cheap decoding of great amounts of DNA. The GEnomic Multi‐tool (GEM) mapper is one of the fastest and most sensitive methods known to date to align such data to a known genomic reference. This unit explains how to use it effectively. © 2015 by John Wiley & Sons, Inc.