Regioselective synthesis of spiro naphthofuranone-pyrazoline via a [3+2] cycloaddition of benzoaurones with nitrile imines. Issue 31 (31st July 2020)

• Record Type: Journal Article
• Authors: Su, Yingpeng; Ma, Chenglong; Zhao, Yanan; Yang, Caixia; Feng, Yawei; Wang, Ke-Hu; Huang, Danfeng; Huo, Congde; Hu, Yulai
• Is Part Of: Tetrahedron. Volume 76:Issue 31/32(2020)
• Publication Date: 2020-07-31
• Subjects: Spirocyclic compound -- [3+2] cycloaddition -- Benzoaurone -- Nitrile imine -- Pyrazoline; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tet.2020.131355
• Languages: English
• ISSNs: 0040-4020

Abstract

Graphical abstract: Image 1 Highlights: A regioselective [3 + 2] cycloaddition reaction of benzoaurones with nitrile imines was developed. A series of compelling spiro [naphthofuran-2, 3′-pyrazoline]-3-ones were efficiently obtained. The reaction displayed good gram-scale capacity.