Multiple sensory illusions are evoked during the course of proton therapy. (August 2020)
- Record Type:
- Journal Article
- Title:
- Multiple sensory illusions are evoked during the course of proton therapy. (August 2020)
- Main Title:
- Multiple sensory illusions are evoked during the course of proton therapy
- Authors:
- Narici, Livio
Titova, Elena
Obenaus, André
Wroe, Andrew
Loredo, Lilia
Schulte, Reinhard
Slater, Jerry D.
Nelson, Gregory A. - Abstract:
- Abstract: Visual illusions from astronauts in space have been reported to be associated with the passage of high energy charged particles through visual structures (retina, optic nerve, brain). Similar effects have also been reported by patients under proton and heavy ion therapies. This prompted us to investigate whether protons at the Loma Linda University Proton Therapy and Research Center (PTRC) may also affect other sensory systems beside evoking similar perceptions on the visual system. A retrospective review of proton radiotherapy patient records at PTRC identified 29 sensory reports from 19 patients who spontaneously reported visual, olfactory, auditory and gustatory illusions during treatment. Our results suggest that protons can evoke neuronal responses sufficient to elicit conscious sensory illusion experiences, in four senses (auditory, taste, smell, and visual) analogous to those from normal sensory inputs. The regions of the brain receiving the highest doses corresponded with the anatomical structures associated with each type of illusion. Our findings suggest that more detailed queries about sensory illusions during proton therapy are warranted, possibly integrated with quantitative effect descriptions (such as electroencephalography) and can provide additional physiological basis for understanding the effects of protons on central nervous system tissues, needed for radiation risk assessment in advance of deep space human exploration.
- Is Part Of:
- Life sciences in space research. Volume 26(2020)
- Journal:
- Life sciences in space research
- Issue:
- Volume 26(2020)
- Issue Display:
- Volume 26, Issue 2020 (2020)
- Year:
- 2020
- Volume:
- 26
- Issue:
- 2020
- Issue Sort Value:
- 2020-0026-2020-0000
- Page Start:
- 140
- Page End:
- 148
- Publication Date:
- 2020-08
- Subjects:
- visual -- gustatory -- olfactory -- auditory -- radiation -- patients -- space -- brain
Space biology -- Periodicals
571.0919 - Journal URLs:
- http://www.sciencedirect.com/science/journal/22145524 ↗
http://www.sciencedirect.com/ ↗ - DOI:
- 10.1016/j.lssr.2020.04.006 ↗
- Languages:
- English
- ISSNs:
- 2214-5524
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 13567.xml