Calcium loss in sweat does not stimulate PTH release: A study of Bikram hot yoga. (June 2020)

• Record Type: Journal Article
• Authors: Mathis, Shannon L.; Pivovarova, Aleksandra I.; Hicks, Sarah M.; Alrefai, Hasan; MacGregor, Gordon G.
• Is Part Of: Complementary therapies in medicine. Volume 51(2020)
• Publication Date: 2020-06
• Subjects: Bikram hot yoga -- Sweat -- Calcium -- PTH -- CTX-I; Alternative medicine -- Periodicals; Complementary Therapies -- Periodicals; Médecines parallèles -- Périodiques; Thérapeutique -- Périodiques; Alternative medicine; Electronic journals; Periodicals; 615.5
• DOI: 10.1016/j.ctim.2020.102417
• Languages: English
• ISSNs: 0965-2299

Abstract

Highlights: A large amount of sweat is lost during 90 min of Bikram hot yoga which concentrates the extracellular fluid and blood. Serum ionized calcium increased after Bikram hot yoga triggering a decrease in PTH secretion. There is no evidence that Bikram hot yoga stimulates bone loss to maintain extracellular fluid calcium levels. Abstract: It has been hypothesized that sweat loss during exercise causes a disruption in calcium homeostasis that activates bone resorption and over time leads to low bone mineral density. The purpose of this small pilot study was to determine whether dermal calcium loss from a bout of excessive sweating during light intensity physical activity triggers an increase in biomarkers of bone resorption. Biochemical markers related to bone homeostasis were measured before and after a 90 min Bikram hot yoga practice performed in a room heated to 105 °F with 40 % humidity. Participants were five females with a mean age of 47.4 ± 4.7 years. Nude body weight, serum total calcium (Ca 2+ ), free ionized calcium, albumin, parathyroid hormone (PTH) and CTX-I were measured before and after a Bikram hot yoga practice. Mean estimated sweat loss was 1.54 ± 0.65 L, which elicited a 1.9 ± 0.9 % decrease in participant's body weight. Mean Ca 2+ concentration in sweat was 2.9 ± 1.7 mg/dl and the estimated mean total calcium lost was 41.3 ± 16.4 mg. Serum ionized Ca 2+ increased from 4.76 ± 0.29 mg/dl to 5.35 ± 0.36 mg/dl after the Bikram hot yoga practice ( p = 0.0118). Serum PTH decreased from pre- 33.9 ± 3.3 pg/ml to post- 29.9 ± 2.1 pg/ml yoga practice ( p = 0.0015) when adjusted for hemoconcentration (PTHADJ ), implying a decrease in PTH secretion. We conclude that calcium loss in sweat during 90 min of Bikram hot yoga did not trigger an increase in PTH secretion and did not initiate bone resorption.