Prime Editing: Game Changer for Modifying Plant Genomes. (August 2020)

• Record Type: Journal Article
• Authors: Marzec, Marek; Hensel, Goetz
• Is Part Of: Trends in plant science. Volume 25:Number 8(2020)
• Page Start: 722
• Page End: 724
• Publication Date: 2020-08
• Subjects: CRISPR-Cas9 -- genome editing -- custom endonucleases -- targeted mutagenesis; Botany -- Periodicals; Botanique -- Périodiques; Botany; Periodicals; 580.5
• DOI: 10.1016/j.tplants.2020.05.008
• Languages: English
• ISSNs: 1360-1385

Abstract

Abstract : Prime editing, developed by Anzalone et al ., brings genome editing to a new level, because this approach allows introduction of all mutation types, including insertions, deletions, and all putative 12 types of base-to-base conversions. Previously tested in human cells, this technique has been adapted for use in plants by Lin et al .