Catechins and lignan from the flower buds of Rosa chinensis Jacq. (August 2020)

• Record Type: Journal Article
• Authors: Liu, Ying; Lu, Zhao; Wang, Mei; Chen, Yang; Zhan, Rui; Shao, Li-Dong; Chen, Ye-Gao
• Is Part Of: Phytochemistry letters. Volume 38(2020)
• Page Start: 46
• Page End: 48
• Publication Date: 2020-08
• Subjects: Rosa chinensis Jacq. -- rosacatechins -- flower buds -- flavonoids; Botanical chemistry -- Periodicals; Chimie végétale -- Périodiques; 572.205
• DOI: 10.1016/j.phytol.2020.05.004
• Languages: English
• ISSNs: 1874-3900

Abstract

Graphical abstract: Highlights: The flower buds of Rosa chinensis Jacq. were investigated. Five catechins (1-5 ) and a lignan (6 ) were isolated. Rosacatechin A (1 ) is a catechin analogue with 8- n- butoxycarbonyl substitution. The absolute configuration of 1 was determined as 2 R, 3 S . Abstract: Five catechins (1 -5 ) including a new compound rosacatechins A (1 ) and a new natural product (2 ), along with a lignan (6 ) were isolated from 70% aqueous acetone extracts of the flower buds of Rosa chinensis Jacq. Their structures were elucidated by extensive spectroscopic analysis. No cytotoxicity was detected on the anti-proliferative assay of these compounds against five cancer cell lines.