Genetically encoded biosensors based on innovative scaffolds. (August 2020)

• Record Type: Journal Article
• Authors: Moeyaert, Benjamien; Dedecker, Peter
• Is Part Of: International journal of biochemistry & cell biology. Volume 125(2020)
• Publication Date: 2020-08
• Subjects: Genetically encoded biosensors -- Fluorescent proteins -- Selflabeling enzymes -- Cell imaging -- Protein engineering; Biochemistry -- Periodicals; Cytology -- Periodicals; Biochemistry -- Periodicals; Cell Biology -- Periodicals; Biochimie -- Périodiques; Cytologie -- Périodiques; Biochimie; Cytologie; Biochemistry; Cytology; Ressource Internet (Descripteur de forme); Périodique électronique (Descripteur de forme); Periodicals; 572.05
• DOI: 10.1016/j.biocel.2020.105761
• Languages: English
• ISSNs: 1357-2725

Abstract

Abstract: Genetically encoded biosensors are indispensable tools for visualizing the spatiotemporal dynamics of analytes or processes in living cells in vitro and in vivo. Their widespread adaptation has gone hand in hand with the development of sensors for new analytes or processes and improved functionality and robustness. In this review, we highlight some of the recent advances in genetically encoded biosensor development, with a special focus on novel and innovative scaffolds that will lead to new possibilities in the future.