Colorectal neuroendocrine tumors: A case series. (2020)

• Record Type: Journal Article
• Authors: Warsinggih, ; Liliyanto, ; Prihantono, ; Ariani, Gusti Deasy Wilda; Faruk, Muhammad
• Is Part Of: International journal of surgery case reports. Volume 72(2020)
• Page Start: 411
• Page End: 417
• Publication Date: 2020
• Subjects: Neuroendocrine tumor -- Colorectal cancer -- Peritonitis -- Large bowel obstruction -- Case series; Surgery -- Periodicals; Surgical Procedures, Operative -- Periodicals; Surgery; Electronic journals; Periodicals; 617.005
• DOI: 10.1016/j.ijscr.2020.06.030
• Languages: English
• ISSNs: 2210-2612

Abstract

Highlights: Neuroendocrine tumors (NET) of the colon and sigmoid colon are uncommon compared to colorectal adenocarcinoma. The incidence of NETs has increased, probably due to improved diagnosis and the availability of very specific and sensitive modalities. Here, we report a serial case of Gastrointestinal NET (GI-NET) found in the descending colon and sigmoid colon. Abstract: Introduction: Neuroendocrine tumors (NET) of the colon and sigmoid colon are uncommon compared to colorectal adenocarcinoma. Few reports have been made of NET of the colon and sigmoid colon that presents with peritonitis and large bowel obstruction. Case presentation: Here, we report two cases of NET of the colon and sigmoid colon, which were diagnosed and treated at our institution. In our first case, a 66-year-old man with a history of abdominal distension was diagnosed with NET via histopathology of the sigmoid colon. The second case involved a 45-year-old woman with the chief complaints of abdominal distention and inability to defecate; specimen histopathology of the descending colon showed neuroendocrine carcinoma features. Clinical outcome was very poor in our patients: eight months after the resection, the second patient demonstrated a sign of metastasis on the liver. Conclusion: An uncommon case of colon and sigmoid colon carcinoma with neuroendocrine and diagnostic difficulties precludes an exact description of the initial diagnostic criteria and management. Thus, our case series offers an overview of initial symptoms, radiological and histopathological features for early diagnosis, and proper management of NET.