Memorability of photographs in subjective cognitive decline and mild cognitive impairment: Implications for cognitive assessment. Issue 1 (1st December 2019)

• Record Type: Journal Article
• Authors: Bainbridge, Wilma A.; Berron, David; Schütze, Hartmut; Cardenas‐Blanco, Arturo; Metzger, Coraline; Dobisch, Laura; Bittner, Daniel; Glanz, Wenzel; Spottke, Annika; Rudolph, Janna; Brosseron, Frederic; Buerger, Katharina; Janowitz, Daniel; Fliessbach, Klaus; Heneka, Michael; Laske, Christoph; Buchmann, Martina; Peters, Oliver; Diesing, Dominik; Li, Siyao; Priller, Josef; Spruth, Eike Jakob; Altenstein, Slawek; Schneider, Anja; Kofler, Barbara; Teipel, Stefan; Kilimann, Ingo; Wiltfang, Jens; Bartels, Claudia; Wolfsgruber, Steffen; Wagner, Michael; Jessen, Frank; Baker, Chris I.; Düzel, Emrah;
• Is Part Of: Alzheimer's & dementia. Volume 11:Issue 1(2019)
• Page Start: 610
• Page End: 618
• Publication Date: 2019-12-01
• Subjects: Alzheimer's disease (AD) -- Subjective cognitive decline (SCD) -- Mild cognitive impairment (MCI) -- Memorability -- Diagnostic assessment -- Image analysis; Alzheimer's disease -- Periodicals; Alzheimer's disease -- Diagnosis -- Periodicals; Dementia -- Periodicals; Dementia -- Diagnosis -- Periodicals; 616.831
• DOI: 10.1016/j.dadm.2019.07.005
• Languages: English
• ISSNs: 2352-8729

Abstract

Abstract: Introduction: Impaired long‐term memory is a defining feature of mild cognitive impairment (MCI). We tested whether this impairment is item specific, limited to some memoranda, whereas some remain consistently memorable. Methods: We conducted item‐based analyses of long‐term visual recognition memory. Three hundred ninety‐four participants (healthy controls, subjective cognitive decline [SCD], and MCI) in the multicentric DZNE‐Longitudinal Cognitive Impairment and Dementia Study (DELCODE) were tested with images from a pool of 835 photographs. Results: We observed consistent memorability for images in healthy controls, SCD, and MCI, predictable by a neural network trained on another healthy sample. Looking at memorability differences between groups, we identified images that could successfully categorize group membership with higher success and a substantial image reduction than the original image set. Discussion: Individuals with SCD and MCI show consistent memorability for specific items, while other items show significant diagnosticity. Certain stimulus features could optimize diagnostic assessment, while others could support memory.