Clinical profile of symptomatic congenital cytomegalovirus infection: cases from a tertiary hospital in north India. (July 2020)

• Record Type: Journal Article
• Authors: Bhattacharya, Deepanjan; Panigrahi, Inusha; Chaudhry, Chakshu
• Is Part Of: Tropical doctor. Volume 50:Number 3(2020)
• Page Start: 282
• Page End: 284
• Publication Date: 2020-07
• Subjects: Cytomegalovirus -- microcephaly -- ventriculomegaly -- TORCH; Tropical medicine -- Periodicals; Medical care -- Developing countries -- Periodicals; Developing Countries -- Periodicals; Tropical Medicine -- Periodicals; Tropische geneeskunde; 616.9883
• DOI: 10.1177/0049475520923491
• Languages: English
• ISSNs: 0049-4755

Abstract

We retrospectively analysed the records of nine infants with polymerase chain reaction proven congenital cytomegalovirus (CMV) infection, of which 66% were born preterm. Microcephaly was a universal finding, followed by hepatosplenomegaly in 89%, while chorioretinitis was seen in only 44% cases. The mean age at diagnosis was 3.5 months. Neuroimaging was abnormal in 78%, with ventriculomegaly being the most common finding followed by T2/FLAIR white matter abnormalities, periventricular cysts and intracranial haemorrhage.