Acquired von Willebrand Syndrome in an Infant With Coarctation of the Aorta and Williams Syndrome. Issue 4 (July 2020)

• Record Type: Journal Article
• Authors: Cochran, Clinton D.; Madani, Rohit S.; Peltier, Daniel; Pipe, Steven; Owens, Sonal T.
• Is Part Of: World journal for pediatric & congenital heart surgery. Volume 11:Issue 4(2020)
• Page Start: NP91
• Page End: NP93
• Publication Date: 2020-07
• Subjects: coarctation of the aorta -- acquired von Willebrand syndrome -- congenital heart disease -- Williams syndrome -- blood -- coagulation/anticoagulation; Pediatric cardiology -- Periodicals; Congenital heart disease in children -- Periodicals; Heart -- Abnormalities -- Surgery -- Periodicals; Heart -- Surgery -- Periodicals; Heart Defects, Congenital -- surgery -- Periodicals; Cardiac Surgical Procedures -- Periodicals; Child -- Periodicals; Adult -- Periodicals; 618.9212
• DOI: 10.1177/2150135117733942
• Languages: English
• ISSNs: 2150-1351

Abstract

An infant with coarctation of the aorta and Williams syndrome was noted to have petechiae in cardiology clinic prior to planned surgical intervention. Workup revealed acquired von Willebrand syndrome secondary to the high shear force generated by the aortic coarctation. He was treated with intra- and postoperative Humate P; there were no postoperative bleeding complications. His acquired von Willebrand syndrome resolved postoperatively.