Staff sensitisation to therapeutic monoclonal antibodies resulting from workplace exposure: A case report. (July 2020)

• Record Type: Journal Article
• Authors: Barrott, Lisa; Foreman, Emma
• Is Part Of: Journal of oncology pharmacy practice. Volume 26:Number 5(2020)
• Page Start: 1282
• Page End: 1284
• Publication Date: 2020-07
• Subjects: Bevacizumab -- hypersensitivity -- monoclonal antibody -- occupational exposure; Cancer -- Chemotherapy -- Periodicals; Clinical pharmacology -- Periodicals; 616.994061
• DOI: 10.1177/1078155220901750
• Languages: English
• ISSNs: 1078-1552

Abstract

Monoclonal antibodies were introduced to clinical practice in 1980s and play a vital role in a variety of diseases and clinical interventions including cancer, inflammatory disease, and ophthalmologic disease. There is a lack of substantial research or evidence on the effect of occupational exposure on staff, leading many staff to have significant concerns about what is a safe level of exposure, especially given their increasing availability and use. This report describes a case in which a nurse became sensitised to monoclonal antibodies as a result of preparing and administering them in a clinical area, and the subsequent actions taken in response to the incident to reduce the risk to staff.