Antisynthetase syndrome in pregnancy: A case and review of the literature. (June 2020)

• Record Type: Journal Article
• Authors: Green, Lauren J; O'Neill, Lorraine; Frise, Charlotte J
• Is Part Of: Obstetric medicine. Volume 13:Number 2(2020:Jun.)
• Page Start: 96
• Page End: 100
• Publication Date: 2020-06
• Subjects: Antisynthetase syndrome -- inflammatory myopathy -- pregnancy -- anti-Ro antibodies; Pregnancy -- Complications -- Periodicals; Obstetrics -- Periodicals; 618.2
• DOI: 10.1177/1753495X18808646
• Languages: English
• ISSNs: 1753-495X

Abstract

Antisynthetase syndrome is a rare autoimmune, multisystem, inflammatory condition, characterised by autoantibodies against aminoacyl tRNA synthetases. The predominant features are myositis and interstitial lung disease but other symptoms such as Raynaud's phenomenon may also be present. Described here is a 36-year-old woman with antisynthetase syndrome who planned and underwent a successful pregnancy, during which a multidisciplinary team approach secured a good outcome for both mother and baby.